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yitC [2019-07-31 08:28:14]
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yitC [2019-07-31 08:28:14]

mother cell-specific [SW|sporulation] protein, similar to 2-phosphosulfolactate phosphatase
locus
BSU_10940
pI
5.22
mw
24.51 kDa
protein length
228 aa Sequence Blast
gene length
687 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]

    • Gene

    Coordinates
    1,172,650 → 1,173,336

    The protein

    Protein family

  • ComB family (single member, according to UniProt)

    • Structure

  • [PDB|1VR0] (from Clostridium acetobutylicum, 31% identity) [pubmed|16927339]

    • Additional information

  • The gene is annotated in KEGG as ortholog of 2-phosphosulfolactate phosphatase EC 3.1.3.71. In Swiss-Prot the protein is marked as “probable 2-phosphosulfolactate phosphatase”. No EC annotation is available in MeMetaCyc.No literature/experimental evidence supporting the annotation is available. [Pubmed|19935659]

    • Expression and Regulation

    Operons

    genes
    [gene|FA7147930DA90604BE2B4837A8A4393F72498AB1|yitC]-[gene|97156E7227E298B0DECC9AAC1411D0DAF3420C29|yitD]
    description
    [Pubmed|22383849]

    sigma factors

  • [protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, [Pubmed|15383836], in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon]
  • [protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK]: sigma factor, [Pubmed|15699190,15383836], in [regulon|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK regulon]

    • regulation

  • expressed during [SW|sporulation] in the mother cell ([protein|search|SigE], [protein|search|SigK]) [Pubmed|15699190,15383836]
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    Biological materials

    Mutant

  • MGNA-B177 (yitC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1176 NBRP B. subtilis, Japan]
  • BKE10940 (Δ[gene|FA7147930DA90604BE2B4837A8A4393F72498AB1|yitC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE10940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATACTACCTCTCCTTGGGC, downstream forward: _UP4_CCAACGATAGAGAGGGTCAT
  • BKK10940 (Δ[gene|FA7147930DA90604BE2B4837A8A4393F72498AB1|yitC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK10940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATACTACCTCTCCTTGGGC, downstream forward: _UP4_CCAACGATAGAGAGGGTCAT

    • References

  • 15699190,15383836,27766092,16927339